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Integrative Rheumatology & Functional Medicine · Mumbai + Online

Struggling with an Autoimmune or Chronic Inflammatory Condition?

Psoriasis Lichen Planus & other Skin Conditions Rheumatoid Arthritis Ankylosing Spondylitis SLE (Lupus) Hashimoto’s Thyroiditis Sjogren’s Syndrome MS etc.

(Support provided alongside appropriate medical care)

Educational information only. Care is individualized and results vary.

We ask every new patient to watch the master class before booking. It explains the science, the method, the monitoring, and what to expect, so your consultation starts from a place of clarity.

Hands affected by psoriasis, an autoimmune skin condition
Thyroid illustration representing Hashimoto's thyroiditis and thyroid conditions
Person with chronic neck and back pain and inflammatory stiffness
Person holding a red, inflamed painful knee, representing arthritis and chronic joint pain
Doctor-led team· Rheumatology + Functional Medicine· Evidence-informed & referenced· Mumbai + Online worldwide

A Ray of Hope

Our Master Class · Please watch first (Mandatory) ↓
Evidence-Informed Overview:

Vitamin D & Functional Nutrition in Autoimmune Support

These videos are educational and not medical advice.

Why Vitamin D benefits: evidence-informed overview of autoimmune supportVideo 1
Why Vitamin D Benefits? Evidence-Informed Overview: Autoimmune Support
How Vitamin D dosage is individualized and why self-prescribing is riskyVideo 2
How Vitamin D Dosage is Individualized: Why Self-Prescribing is Risky
The Coimbra protocol of Vitamin D in managing autoimmune diseases and what Vitamin D resistance isVideo 3
The Coimbra Protocols of Vitamin D in Managing Autoimmune Diseases || What is Vitamin D Resistance?
Cofactors and safety monitoring: evidence-informed overviewVideo 4
Cofactors and Safety Monitoring: Evidence-Informed Overview
Educational case discussions on autoimmune support, no outcomes are guaranteedVideo 5
Educational Case Discussions on Autoimmune Support (No outcomes are guaranteed)
Is this for you?

Who Should Consult us?

You may benefit from a consult if you:

Support for lifestyle and chronic conditions such as diabetes, thyroid issues, migraines, fatigue, sleep and breathing disorders, and chronic musculoskeletal discomfort
Diagnosed or Undiagnosed Sleep Disorders, Insomnia, & Snoring. Suffering through Troubled Sleep, Sleep Apnea, Sleep Breathing Disorders, Insomnia etc and even when you do sleep, you wake up tired, fatigued, in Pains with Gut Dysbiosis etc.
Diagnosed with a Chronic Inflammatory, Autoimmune, Chronic Pain Condition but Only prescribed with Pain Killers & Steroids with Few Exercises without any lasting relief.
Partial or No Success with different Alternatives and Main Stream modalities. Tired of Expensive & Stringent Coaching & Diet Programmes without real Lasting relief.

Meet the Experts

Dr. Krushal Pabari, MBBS MD, rheumatology and musculoskeletal specialist at Cure4Pain

Dr. Krushal Pabari

[MBBS, MD, PGCP Rheumatic & Musculo-Skeletal Diseases]
Specialties: Rheumatology & Musculoskeletal Care, Functional & Orthomolecular Medicine
  • Provides integrative care for autoimmune, inflammatory, and musculoskeletal health concerns.
  • Focuses on personalized patient assessment, safety-first planning, and multidisciplinary coordination.
  • Supports patients with lifestyle and chronic health challenges using evidence-informed approaches.
  • Experienced in functional medicine strategies and biochemical optimization as part of overall care.
AT. Chintan Dalal, BNYS naturopath and orthopedic acupuncturist at Cure4Pain, Mumbai

AT. Chintan Dalal

[BNYS, PGD Acupuncture, R.AP]
Specialties: Integrative Functional & Nutritional Care, Musculoskeletal & Spine Support
  • Offers integrative approaches for autoimmune, metabolic, and musculoskeletal health concerns.
  • Supports spinal and orthopedic wellness with acupuncture and functional care techniques.
  • Designs individualized programs to enhance mobility, resilience, and overall well-being.
  • Coordinates with treating physicians when needed to ensure safe, multidisciplinary care.

AT. Chintan Dalal is a Naturopath, TCM herbalist, and orthopedic acupuncturist with a focus on functional and orthomolecular medicine and Coimbra-inspired Vitamin D protocol principles.

Based in Mumbai, India, he works with a multidisciplinary team where modern diagnostics and evidence-informed research meet the practical wisdom of Eastern healing systems and conservative, natural care strategies.

Alongside him, Dr Krushal Pabari (MBBS, MD), specialist in rheumatology and musculoskeletal disorders, supports patients with autoimmune and chronic inflammatory conditions using a safety-first, clinically monitored approach that integrates medical evaluation with functional and nutritional strategies where appropriate.

Together, the team supports patients living with chronic and complex conditions such as rheumatoid arthritis, type 2 diabetes support, thyroid dysfunction support, fibromyalgia, and cervical and lumbar spine disorders. Plans are individualized, and outcomes vary by person and severity.

The approach

Why Vitamin D & Functional Nutrition Therapy for Autoimmune Disorders & Chronic Disorders?

How does Vitamin D affect autoimmune diseases?
Vitamin D plays a role in immune regulation and inflammatory signaling in the body. Research suggests it may influence immune balance and cellular communication involved in inflammatory responses. Its effects can vary based on individual factors such as baseline levels, overall health, genetics, and clinical context. Vitamin D is not a standalone treatment for autoimmune diseases, and its role should be considered as part of a broader, clinician-guided approach.
How is vitamin D dosing individualized in clinical practice?
Vitamin D dosing is determined on a case-by-case basis after reviewing an individual’s diagnosis, medical history, symptoms, current medications, lifestyle factors, and relevant laboratory markers. There is no single dose that is suitable for everyone. Supplementation, when considered, should always be clinician-guided and regularly monitored. Self-prescribing is not advised.
Why might vitamin D requirements differ between individuals?
Vitamin D needs can vary due to differences in absorption, metabolism, baseline nutrient levels, immune activity, body composition, sun exposure, and existing health conditions. Because of this variability, requirements may differ significantly from person to person, and any approach must be personalized rather than standardized.
How do clinicians determine vitamin D dosage on a case-by-case basis?
Clinicians consider factors such as laboratory results, symptom patterns, medical history, kidney function, calcium balance, and overall health status. Dosing decisions are made cautiously and adjusted over time based on clinical response and monitoring. This process helps reduce risk and supports safety.
What safety considerations are important with vitamin D-based approaches?
Safety depends on proper patient selection, individualized dosing, and appropriate monitoring. Vitamin D-based approaches are not suitable for everyone. Regular follow-up and laboratory evaluation may be required to reduce potential risks. Individuals should never start, stop, or change supplementation without professional guidance.
How about the kidneys?
Kidney health is an important consideration when evaluating any nutritional or supplementation-based approach. Individual medical history, existing kidney conditions, hydration status, and laboratory parameters are reviewed as part of personalized care planning. Dietary guidance, hydration recommendations, and supplement use are individualized and adjusted based on clinical context. Individuals with a history of kidney concerns should inform their healthcare provider so that care can be planned appropriately. This approach may not be suitable for everyone.
What is the recommended diet on this protocol?
Dietary guidance is individualized and may focus on balanced nutrition, adequate hydration, and foods that support overall metabolic and inflammatory health. Recommendations vary depending on individual health conditions, nutritional status, and clinical needs. No single diet is universally recommended for all individuals.
What other supplements are a part of the protocol?
When appropriate, clinicians may consider additional nutrients or supplements as part of a personalized care plan. Selection and timing depend on individual needs, existing medications, laboratory findings, and tolerance. Supplements are introduced cautiously and are not the same for everyone.
How is the treatment monitored?
Monitoring is tailored to the individual and may include periodic clinical reviews and laboratory assessments when clinically indicated. Monitoring helps guide adjustments to the care plan and supports safety. Individuals should not start, stop, or change supplements without professional guidance.
What are the required lab tests?
Laboratory testing may be considered on an individual basis to support clinical assessment and monitoring. Depending on medical history and evaluation, examples of tests that may be reviewed include vitamin D levels, parathyroid hormone (PTH), calcium parameters (including ionized calcium when indicated), and other relevant nutritional or metabolic markers. Testing decisions, frequency, and interpretation are individualized and guided by the treating clinician. Self-testing or self-interpretation is not recommended. Vitamin D or other supplements should not be started or modified without professional guidance. Any use is individualized and may involve coordinated nutritional planning, hydration considerations, and monitoring based on clinical context and laboratory findings. This approach may not be appropriate for everyone.

Note: This information is for general education only and does not replace medical diagnosis or treatment. Results vary by individual. Do not stop or change prescribed treatment without consulting your treating physician. If you experience emergency symptoms, seek urgent medical care.

Some Studies

The following references are provided for general educational awareness only and do not imply treatment outcomes.

Vitamin D in Autoimmunity: Molecular Mechanisms and Therapeutic Potentials

In many autoimmune diseases.

Frontiers in Immunology, Jan 2017 Read source →

Vitamin D Resistance as a Possible Cause of Autoimmune Diseases

A Hypothesis Confirmed by a Therapeutic High-Dose Vitamin D Protocol.

Front. Immunol., 07 April 2021 Read source →

Safety Data in Autoimmune Diseases with High-Dose Vitamin D3 per the “Coimbra Protocol”

According to the “Coimbra Protocol”.

Nutrients, 14(8), April 2022 Read source →

Selected scientific literature discussing Vitamin D and immune function

A 21st century evaluation of the safety of oral vitamin D.

Nutrition, April 2012 Read source →

Vitamin D levels of 60-80 ng/ml needed to prevent cancer

Toxicity unlikely below levels of 150 ng/ml.

Anticancer Research, 2011 Read source →

Vitamin D3 Ameliorates Th17 Autoimmunity via Transcriptional Modulation of Interleukin-17A

Mechanistic modulation of Th17 inflammatory pathways.

American Society for Microbiology, July 2011

Psoriasis: prolonged high-dose vitamin D in vitiligo and psoriasis

In 2013, a study assessed the effect of prolonged administration of high-dose vitamin D on the clinical course of vitiligo and psoriasis. The patients significantly improved, with no signs of toxicity observed.

Finamor, Danilo C; Coimbra. Dermato-Endocrinology 5.1 (2013): 222-234.

Psoriasis case series (2022) by Dr. Renu Mahtani and team

In 2022, a case series published by Dr. Renu Mahtani and team on psoriasis showed significant improvement. Daily Oral Vitamin D3 without Concomitant Therapy in the management of Psoriasis: A case series.

Clinical Immunology Communications. 2022; 1(2): 17-22. Read source →

Multiple Sclerosis: escalating doses of vitamin D over six months

Patients of MS were given escalating doses of vitamin D for six months, to a maximum of 40,000 IU daily, then gradually lowered over the next six months, averaging out to 14,000 IU daily for the year. The patients given high-dose vitamin D had lower relapse rates, and their T cell activity dropped significantly, compared to the lower-dose group.

Burton, Jodie. “Is Vitamin D a Ray of Hope for Patients With MS?” Neurology Reviews 17.7 (2009): 1-16.

SLE & RA: vitamin D levels negatively correlated with disease activity

The authors found that vitamin D levels were negatively correlated with disease activity. In other words, the more vitamin D in the blood, the lower the disease activity, and vice versa.

Rovin, Brad H.; Vitamin D Deficiency As Marker for Disease Activity and Organ Damage in SLE. Arthritis Rheum 2011;63 Suppl 10:2276.

Resources: Videos

Why Vitamin D therapy for autism is a game changer, Cure4Pain

Why Vitamin D Therapy for Autism is a Game Changer | Cure4Pain x Natsayi Dunira

Watch on YouTube →
Reversing rheumatoid arthritis, the root cause and Vitamin D solution, clinical masterclass

Reversing Rheumatoid Arthritis: The Root Cause & Vitamin D Solution (Clinical Masterclass)

Watch on YouTube →
Multiple sclerosis and Vitamin D, why standard doses often fail

Multiple Sclerosis & Vitamin D: Why Standard Doses Often Fail

Watch on YouTube →
Allergic rhinitis treatment, a game changer approach that works

Allergic Rhinitis Treatment: Game Changer Approach That Works

Watch on YouTube →
▶ Watch more on our YouTube channel

We regularly add new talks, patient-education case discussions and research breakdowns on Vitamin D, the Coimbra protocol and autoimmune care. Subscribe to follow along.

Essential Points to Note

About Natural Scientific Therapy with Vitamin D & Nutraceuticals for AutoImmune Disorders.

It is NOT Casual Supplementation
Vitamin D therapy is different from vitamin D supplementation. Vitamin D is to be taken regularly in doses higher than what is generally advised for correcting its deficiency. Micronutrients and vital minerals like magnesium will be given as cofactors to biologically activate vitamin D. All supplements may not be started simultaneously. They can be introduced, case to case, one at a time. Buying any supplement and taking them casually will not help. Quality matters, formulations matter.
Therapy has to be monitored
Periodic testing of PTH (parathyroid hormone) will be done to help decide and edit the dose of vitamin D for the individual. Be sure you have watched the video shared, VITAMIN D: THERAPEUTIC POTENTIALS IN AUTOIMMUNITY. Vitamin D toxicity is not seen if hypercalcemia (higher than normal blood calcium levels) can be prevented. Therefore, ionised blood calcium levels will be monitored too, VITAMIN D TOXICITY: AN UNMERITED FEAR THAT IS WEAKENING OUR IMMUNE SYSTEM. Based on the ionised calcium levels, dietary tips will be advised to prevent hypercalcemia. Oral calcium supplements are usually stopped as there is enough calcium in our diet which gets absorbed well once vitamin D is in adequate functioning levels.
Its not a one size fit for all protocol but a personalized approach
Based on individual response for the same disease, doses have to be fine tuned. As the immune system of patients with autoimmune diseases is working haywire, they can respond negatively to almost anything including supplements. Then the supplement will have to be changed as per the individual. The health of gut matters; Gut infestations need correction for supplements to get absorbed and control the chronic inflammation that seeds from unhealthy gut. Gut medicines will be prescribed if needed.
Patience and remaining connected helps
Most patients come frustrated and tired. Supplements take time to work. Positive changes happen eventually. It takes at least 3-6 months to find the right doses, the sweet spot for an individual. These supplements can be taken along with the conventional therapies going on, as the target of vitamin D therapy is cellular and deeper. One should not stop these therapies on one’s own will. Eventually, the need for steroids, immune suppressants reduces and can be tapered off under supervision. However, the response to vitamin D therapy is better and faster in those who are not taking them.
Your responsibilities to steer your health
To maintain touch with us as advised to be able to fine tune and help better. Periodic check of PTH and ionized calcium levels as advised, to assess the therapy and dietary compliances. This helps in improving and enhancing the benefits too. Being positive and calm as you will learn to steer your own health better with supplements than without them.
To get something different, we have to do something different
Here, it is a scientific approach to correct the root cause rather than just the manifestations. It is definitely more safe than any conventional therapy. Dr. CG Coimbra, Consulting Neurologist, Brazil has trained many doctors globally. It does work but how much for a person, is based on the duration of symptoms and the mindset and attitude of an individual. An open-minded approach shows better results.
Clarity is a must
Feel free to connect for any queries as all steps taken have a valid reason. We will be happy to answer your entire why’s and how’s. Please ask for scientific papers to share with anyone who is interested.

Frequently Asked Questions

How Long Will I Have to Be On this Therapy / Supplements Protocols?
This depends on the type of AutoImmune Disorder. This is a better lifestyle and Natural therapeutics management based Protocol. Response timelines vary significantly based on diagnosis, severity, and individual factors. Some individuals may notice changes earlier, while others require longer-term support. No specific outcome or timeline can be guaranteed. This will be discussed during your consultation after a clear diagnostics arrived at.
Do I have to See You in-person or Online?
Consultations can be availed both in person and Online. This will depend again on case to case basis. We shall intimate you which would be better suited or a hybrid of both.
Will I be asked to Discontinue Any of My Current Medications?
No. Atleast not right away, we asses the overall health of the patient. A integrative approach is used to gently bring healing and harmony. Over time when the right remission is achieved tapering may be suggested depending on case to case basis.
Is this treatment Ayurvedic / Homeopathy / Naturopathy / Allopathy?
This is Not a Ayurvedic / Homeopathy / Naturopathy / Allopathy treatment. It is though Natural Supplementation Therapy which derives its scientific basis from Modern practices. It does fall under Functional Nutritional Therapy & Medicine. The dosage and Potency Nutraceuticals are used for this therapeutic Protocols.
Is this Covered by my Insurance?
This depends on the Insurance Company. You will have to discuss this with them.
What happens if I skip my Doses?
Since this is a Protocol and Lifestyle management, it is strongly recommended Not to Miss or Abruptly Stop the Protocols.
Are there any side-effects?
When practiced under the right care of Trained Experts, and systematic frequent testing, being on the Protocols stringently, there are No Side effects as seen in case of usage of other Drugs comparatively.
Can I see Scientific Published Data / papers / validation of this Therapy?
Yes they are listed above systematically in the Studies & Video Resources Section. Kindly go through all of them in detail.
Can I talk to another Patient for Validation or Reference?
Due to Patient Confidentiality these cannot be shared. For reference we have provided Published Patient case Studies by our Senior Team Members. These are listed in the Studies & Video resources section.
What if I stop or Want to Stop Mid Way?
This is definitely a very personal choice, being a part of a Protocol based Therapy. It is strongly advised to first discuss this with our Experts and slowly taper away the protocols. You will be asked to Fill out and Sign a Detailed Consent Form for the same.
How much Expense will I incur on a Monthly Basis?
This therapy is Not Expensive, since it uses only Nutraceuticals which are readily available OTC. The regular Blood Tests also for the same are Not expensive and can be availed through most Laboratories. Since each patients dosages are different the Expense per month shall vary as per protocols provided to them.
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Information shared in this form is used for clinical assessment and educational purposes only. It does not constitute medical advice or guarantee any outcome.

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1Watch our master class above. We ask every new patient to do this first.
2Book your appointment. This opens your private patient portal.
3Your consultation, personalized plan, reports and ongoing guidance are all handled inside the portal.

Cure4Pain runs a streamlined, portal-based practice. Everything you need is provided inside your patient portal once you book, so there is no phone queue and nothing to chase.

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